Abstract
Synthesis and Antimicrobial Activity of 2- Acetoxy Substituted Phenyl Pyrazolines in Triethanolamine Medium
P.S. Utale*, R. D. Urkude, V. K. Yeotikar and A. G. Doshi
Abstract:
2- Acetoxy Chalcone and aqueous solution of hydrazine hydrate were refluxed in Triethanolamine for 2 hrs. The reaction mixture was cooled,filtered and crystallised from ethanol-acetic acid mixture to get 3 (2-Acetoxy - 5 - Chlorophenyl ) 1- H - 5 - Phenyl -D2- Pyrazolines. All these synthesised new pyrazolines were tested against organisms. The Minimum Inhibitory Concentration ( MIC ) values were determined by using serial dilution method.
Keywords:Synthesis; Pyrazolines; Derivatives
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