Abstract
Net Rearrangements of 4-acetyl-3-(4-substituted phenylamino)-2-(5-nitropyridin-2-yl)isoxazol-5(2H)-ones to Imidazo [1, 2-a]pyridines by Flash-Vacuum-Pyrolysis (F.V.P)
Chalak Azimi* Farhad Sepehraddin and Helal Tahazade
DOI : http://dx.doi.org/10.13005/ojc/290421
Abstract:
4-acetyl-3-(4-substituted phenylamino)-2-(5-nitropyridin-2-yl) isoxazol-5(2H)-ones, rearranged under Flash-Vacuum-Pyrolysis (F.V.P) conditions accompanied by elimination of carbon dioxide to give imidazo[1, 2-a]pyridines in high to excellent yields (90-95%).
Keywords:Isoxazolones;Imidazopyridines;Flash-Vacuum-Pyrolysis
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