Abstract

In continuation of our earlier work in this paper we studied 50 substituted  Benzenesulphonamide using substituent nanofluorobutyl sulphonyl  chloride (C₄F₉SO₂Cl) and pentafluoro benzene sulphonyl chloride (C₆F₅SO₂Cl) Accordingly we have development QSAR model of studied compounds. These models were derived using the parameters Balaban Index, Balaban-type index,(Jhetz, Jhetm, Jhetv, Jhete, Jhetp)  Balaban related index (F,G.) and Randic connectivity index (χ1). The best suitable model is predicted on the basis of Maximum-R² (R-squared).