Abstract

Fentahun Adamu¹ , Sanidhya Upadhyay² , Bipin Chandra Upadhyay¹ and R. K. Upadhyay^1*

Complexes of Cu(II) nitrate and chloride salts with p-chloro-, p-bromo-and p-iodo-anils of 2-thiophene glyoxal, isolated as binary mixtures of isomers, were separated on thin-layers of silica gel. Separation of mixtures in bulk and of their known quantity was done by column chromatography for determination of isomeric composition of isolates. Resolved isomers were identified using correlation of their RF with spectral properties. The effect of chelate ring contraction on RF values has also been investigated.

Thin layer chromatography; column chromatography; ambidentate ligands; Ketoanils; chelates

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