Abstract
Synthesis of Novel Aryl Quinoxaline Derivatives by New Catalytic Methods
Reza Soleymani1 *, Neda Niakan2 , Shohre Tayeb2 and Shirin Hakimi3
Abstract:
Quinoxalines are nitrogenous compounds that widely are used in various industries like paint, pharmaceutical and medicine. Quinoxaline ring is also part of antibiotics structure such as Actinomycin, Lomacin. By using of this synthesis method of these compounds based on condensation of Aryl-1,2-di amine with 1,2-di carbonyl in the Acidic condition, some new compounds was obtained from Quinoxaline family that for the first time some new catalysts was used for increasing of efficiency and reducing of process time. Used catalysts are CrCl2.6H2 O, PbBr2 and CuSO4.5H2O compounds that preparation of these catalysts is economically, cost-effective and saves time. All mechanisms were done in ethanol solvent at room temperature. However, all results suggest a mild and heterogeneous nature of these mechanisms, shorter time of reaction and higher yield or similar to reported old methods.
Keywords:IR; NMR; Quinoxalines; Synthesis; New Catalytic methods
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