Abstract
Synthesis, Characterization and antimicrobial evaluation of New Chalcone Derivatives From3- benzyloxy-4-methoxybenzaldehyde
L. Benmekhbi1,2, S. Mosbah1, A. Khelifa Baghdouch1, L. Bencharif1
DOI : http://dx.doi.org/10.13005/ojc/310317
Abstract:
A series of chalcone derivatives (2a–i) were prepared via the reaction of 3-benzyloxy-4-methoxybenzaldehyde with the appropriately acetophenon derivatives. The structures of all the newchalcone derivatives (2a–i) synthesized in this study were established on the basis of 1H NMR and 13C NMR spectral data, and elemental analyses The antibacterial activitie of the synthesized compounds (2a- i) was carried out by well diffusion and MIC method.
Keywords:chalcone; X-ray analysis; Claisen–Schmidt Condensation; antibacterial activitie
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