ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

An Efficient Synthesis of Functionalized 3-(α-amidobenzyl)-4-hydroxycoumarin Derivatives by ZnO Nanoparticles Promoted Condensation Reaction Between Aromatic Aldehyde, 4-hydroxycoumarin, and Amides

Hossein Anaraki-Ardakani1, Abbas charooseai2

DOI : http://dx.doi.org/10.13005/ojc/310324


Abstract:

An efficient and green protocol for the synthesis of 3-(α-amidobenzyl)-4-hydroxycoumarin derivatives by one pot, three component coupling reaction of aromatic aldehyde, 4-hydroxycoumarin, and amides has been developed using ZnO nanoparticles (NPs) as the catalyst. The procedure is formed in high yields, short reaction time and an environmentally friendly specificity.

Keywords:

4-Hydroxycoumarin; ZnO nanoparticles (NPs); 3-(α-amidobenzyl)-4-hydroxycoumarins; aromatic aldehydes

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