Abstract

Sunita Bajroliya, G. S. Kalwania^*, Savita Choudhary  and  S. Chomal

DOI : http://dx.doi.org/10.13005/ojc/300419

Mn(II) and Co(II) metal complexes have been synthesized with newly synthesized Schiff bases derived from isatin/5-nitroisatin and 3-substituted-4-amino-5-mercapto-1,2,4-triazole by new environmental benign microwave irradiation method as well as conventional method. Reaction achieved by microwave irradiation technique, require drastically reduced reaction time and provide high yield with improved selectivity as compared to conventional method. The synthesized compounds were characterized by elemental analysis as well as spectral studies. The elemental analysis were clearly indicated that ML₂ type complexes have 1:2 stoichiometry (M=metal, L=ligand). The synthesized Schiff bases and their metal complexes screened for antimicrobial activities against selected bacteria and fungi.

Schiff bases; 1; 2; 4-Triazole; Isatin; 5-Nitroisatin; Microwave irradiation; Antimicrobial Complexes

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