Abstract

Maher Khalid and Shireen Mohammed

DOI : http://dx.doi.org/10.13005/ojc/340603

This review highlights recent improvement in trifluoromethylene functionalization processes with CF₃ reagents, includes: Togni’s, Umemoto’s, CF₃SO₂Cl, CF₃I, Yagupol’skii-Umemoto, TMSCF₃, Langlois (CF₃SO₂Na) and clarifies the several designing to result the corresponding trifluoromethylated products. In this article, the selective trifluoromethylation reactions with Togni’s reagents and their analogs are detailed, which work transition metals or photoactivated Ru or Ir catalysts as single electron giver to yield CF₃ radical intermediate species. This issue is to introduce a draft of diverse reports, presenting the modern reaction collect and mechanics produced during the past five years. This task is demanded by the key protocol connected with the trifluoromethylation reactions, designing to sustain researchers a straight forward understanding of such reactions and to award information for further implements.

Diastereoselectivity; Photocatalyst Process; Togni’s Reagent; Trifluoromethylation; Umemoto’s Reagent; Langlois’ Reagent

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