Abstract
A Decade of Development of Ethylidenethiosemicarbazides as Building Blocks for Synthesis of Azoles and Azines (A Review)
Sayed M. Riyadh1,2
, Shojaa Abed El-Motairi1 and Anwar A. Deawaly1
DOI : http://dx.doi.org/10.13005/ojc/340201
Abstract:
This survey represents synthesis of ethylidenethiosemicarbazides, with aryl or heterocyclic moieties, and its utility as building blocks for construction of different heterocyclic compounds such as; thiazoles, thiazolidinones, [1,3,4]thiadiazoles, [1,3,4]triazoles, [1,3]thiazines, pyrimidines, thiazolo[5,4-b]quinoxalines, bis-thiazoles, and bis-pyrazoles. Also, the pharmaceutical applications of ethylidenethiosemicarbazides have been demonstrated.
Keywords:Thiosemicarbazones; Azoles; Azines; Cyclocondensation; Biological Activity
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