ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Diagnosis, Structure, and in the Vitro Antimicrobial  and Antifungal Evaluation of Some Amino Benzoic Acids -Derived Ligand Schiff Base and Their Mixed Complexes with Cu(II), Hg(II), Mn(II) ,Ni(II) and Co(II)

Rehab Kadhem Rahem Al-Shemary, Lekaa Khalid Abdul Karem and Faeza Hasan Ghanim

DOI : http://dx.doi.org/10.13005/ojc/340263


Abstract:

Innovative various Schiff bases and their Co(II), Ni(II) and Cu(II) and Hg(II)  compounds made by the condensation of 4-amino antipyrine with derived aminobenzoic acid (2-aminobenzoic acid, 3-aminobenzoic acid, and 4-aminobenzoic acid ) have been prepared by conventional approaches. These complexes were described by magnetic sensibility analysis, FT-IR spectra, and molar-conductance and elemental analysis. Analytical values appeared which the mixed-ligand complexes presented ratio about 2:1 (ligand: metal) with the chelation 4 or 6. The prepared compounds offered a good effect on the organisms; bacteria Staphylococcus-aurous, Escherichia-coli and fungi C. albicans, A. niger. Also, the biological products signalize which the mixed complexes show objectively worthy performance  compared to all the investigated bacterial strains, and generally the action order of the produced complexes has been characterized as Ni(II) > Cu(II) > L.

Keywords:

Schiff Bases; 4-Aminopyrine; Biological Activity

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