Abstract
Synthesis and Reactions of 2-Substituted 4-Hydrazinobenzofuro [3,2-D] Pyrimidines and Their Antibacterial Activity
S.N. Goled and S.S. Sangapure
Abstract:
The reactions of 2-substituted 4-chlorobenzofuro [3, 2-d] pyrimidine with hydrazine hydrate gave the corresponding hydrazides. The treatment of hydrazides with ethyl acetoacetate, ethyl cyanoacetate and acetyl acetone afforded 4-pyrazolyl benzofuro [3, 2-d] pyrimidines. The condensation of 4-hydrazide with different aldehydes gave arylidene hydrazino derivatives.
Keywords:ethyl acetoacetate; ethyl cyanoacetate; acetyl acetone
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