Abstract

Mohamed Habid Oueslati^1,2, Jalloul Bouajila³ and Hichem Ben Jannet⁴

DOI : http://dx.doi.org/10.13005/ojc/330432

Phytochemical investigation of the roots of Salsolaimbricata allowed to two new bioactive biphenylpropanoids(1) and (2) named biphenylsalsonoidA and B, respectively. Their structures were established through spectroscopic methods (1D and 2D NMR, (ES)-HRMS, and IR).The isolates were tested for their antioxidant activity using DPPH^● and ABTS^●+ assays. 1 and 2 showed a moderate activity towards DPPH (IC₅₀ = 86.5 ± 1.3 and 122.3 ± 0.63 μg/mL, respectively) and ABTS (IC₅₀ = 95 ± 1.5, 137.7 ± 1.2 μg/mL, respectively). The antibacterial effect of the ethyl acetate extract and the isolates were assessed. Resultsobtained revealed that compounds showed important antibacterial activities against S. aureus, S. epidermidis, M. luteus, and E. coli with MIC values ranging from 16 to 32 μg/mL.

Salsolaimbricata; biphenylsalsonoids; NMR; antioxidant activities; antibacterial activities

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