ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis of Hydrazones Schiff Bases and Microbiological Evaluation of Isonicotinoyl Hydrazide with Different Acetophenone

S.R. Kelode1, P.R. Mandlik1 and A.S. Aswar2


Abstract:

A series of hydrazones Schiff bases compounds have been synthesized by reacting isonicotinoyl hydrazide with 2-hydroxy-5-chloro acetophenone, 2-hydroxy-5-methyl acetophenone , 2-hydroxy-5-carboxy acetophenone, 2,5-dihydroxy acetophenone, 2-hydroxy-5-chloro-4-methyl acetophenone, 2-hydroxy-5-chloro-3-nitro acetophenone, 2-hydroxy-5-methyl-3-nitro acetophenone and 2-hydroxy-5-bromo acetophenone. The Schiff bases have been evaluated for the antifungal and antibacterial activities.

Keywords:

Schiff bases; Isonicotinoyl hydrazide; Acetophenone; Antibacterial activities

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