Abstract

N.O. Mahmoodi*, M. Mamaghani and A. Azimi

One-pot synthesis of a series of (1E,4E)-1,5-bis-arylpenta-1,4-dien-3-ones considering as curcumin analogs through the condensation of pentane-2,4-dione with aldehydes in water and base for the fast (5-8min) and high yielding (85- 95%)preparation of dienone systems such as 7a-g are enclosed. The structures of the products were deduced from their elemental analyses and spectroscopic data.

On water; One pot; regioselective; (1E,4E)-1,5-bis-aryl-penta-1,4-dien-3-ones

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