ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis and Antimicrobial Evaluation of 8-[{4- (2-Substituted Phenyl–5-Oxo-Thiazolidin-1-Yl)- 5-Thiobutyl Triazolo} Methoxy] Quinolines

T. Chandra1, S. K. Bhati1, H. Panwar1 and K. P. S. Vishnoi1


Abstract:

Several 8-substituted derivatives of quinoline were synthesized. The structure of the prepared compounds were characterezied by elemental and spectral (I.R.,1H-NMR, Mass) analysis. These molecules were evaluated for their efficacy as antimicrobials in vitro by disc diffusion method against some selected pathogenic strains in compare to gatifloxacin and fluconazole.

Keywords:

Quinolines; antibacterial activity; antifungal activity; toxicity

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