Abstract

A. B. Patil

The antibacterial activities of the ligands, ampicillin (AMP) and cephalexin (CEP) and their binary and ternary complexes using aspartic acid (ASP) as primary ligand with Co (II), Ni (II), Cu (II) and Zn (II) were tested against human pathogenic bacteria using the Kirby-Bauer’s disc diffusion method. The test organisms used are B.subtilis, S.aureus (Gram positive) E.coli and P. aeruginosa (Gram negative). It is observed that the organism, P.aerugonisa is resistant to all the test complexes. The antibacterial activity of binary and ternary complexes of Cu (II is more against E.coli and S. aureus.

Antibacterial activity; transition metal complexes

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