Abstract

M. S. Lunge

Benzanide group containing nitrogen and sulphur heteroacycles have added their own identity and importance in pharmaceutical, medicinal, agricultural and drug sciences. Thiocarbamido heteroacyclic compounds showed noticeable and remarkable applications in industrial, pharmaceutical, medicinal and drug chemistry. Considering all these facts into consideration it was thought interesting to synthesize 2-(3,4,5-trimethoxyphenyl)thiocarbamide/substitutedthiocarbamids by interacting 2-(3,4,5-trimethoxyphenyl)ethamine with various thiourea in isopropanol medium .The justification and identification of the structure of these newly synthesized compounds had been established on the basis of chemical characterization, elemental analysis and through spectral data The antimicrobial activities of this compounds were screened against E. coli, S. typhi, S. abony, P. aeruginosa, B. subtilis, A. niger, and C. albicons pathogens which are not studied up till now.

Substitutedthiocarbamides; 2-(3,4,5-trimethoxyphenyl)ethamine and isopropanol

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