Abstract
Synthesis of 3-Bromo Flavones from 2-Hydroxy-3, 5-Dibromo-4’nitro Dibenzoyl Methane
R.E. Bhadange1 and R. P. Ganorkar2
Abstract:
A new 3-bromo substituted flavones have been synthesized by the reaction of 2- hydroxy-3, 5-dibromo-4'nitro dibenzoyl methane was dissolved in dimethyl formamide (DMF) and pure bromine was added. The mixture was refluxed for 1-3 hours. Then cooled, diluted with ice-cold water and crystallized from alcohol-acetic acid mixture to get 2(4'nitrophenyl)-3,6, 8-tribromo flavones.The structures of all newly synthesized compounds were confirmed on the basis of IR,NMR. The melting points were taken in an open capillary tube.
Keywords:Synthesis; Dibenzoyl methane; Bromo-Flavones
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