ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Vanadatesulfuric Acid-Catalyzed Novel And Eco-Benign One-Pot Synthesis Of Polyhydroquinoline Derivatives Under Solvent-Free Conditions

Masoud Nasr-Esfahani* and Tooba Abdizadeh


Abstract:

A novel and green approach for efficient and rapid synthesis of biologically active polyhydroquinoline derivatives via unsymmetric Hantzsch reaction using Vanadatesulfuric acid (VSA) as a new and recyclable catalyst under solvent-free conditions was reported. The catalyst was characterized by FT-IR, XRD and XRF analysis. The present method offers several advantages such as simple procedure, short reaction time, high yields, simple workup, reusability of the catalyst and simple purification of the products.

Keywords:

aldehyde; 1;3-cyclohexanediones; Heterogeneous catalysis; Polyhydroquinoline; Vanadatesulfuric acid

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