ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis and Characterization of 4-Phenacyloxy Benzaldehyde Derivatives

>Undri Rastuti1,2, Dwi Siswanta1, and Jumina1*

DOI : http://dx.doi.org/10.13005/ojc/320515


Abstract:

Some new 4-phenacyloxy benzaldehyde derivatives (PB1-PB4) have been synthesized through substitution reaction of 4-hydroxy-benzaldehyde derivatives and phenacyl bromide derivatives using triethylamine as the catalyst in the micellar media at room temperature. Physical data from IR, 1H-NMR, 13C-NMR and GC-MS were used to characterize the compounds structure. The yield of the PB1-PB4 compounds was 46-66% with purity of 91-96%. The compounds have been tested as an antibacterial agent.

Keywords:

Phenacyl; phenacyloxy benzaldehyde; micellar; IR; 1H-NMR; 13C-NMR; GC-MS

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