Abstract

Amol Bhendkar*,  A. G. Doshi+,  A. W. Raut

Some new 2-amino-4-(2'-fury1)6-(substituted phenyl) pyrimidine (Iia-f) have been synthesized by action of Guanidine Nitrate on 1-fury1-3-(substituted phenyl)-2-propene-1-one(Ia-f). The title compound (Iia-f) were further treated with nitrous acid to afford 4-(2'-furyl)-6-(substituted phenyl)-2-(l-H) pyrimidinone (IIIa-f). All these newly synthesized compounds have been characterized by spectroscopic data and also screened for antimicrobial activity.

Synthesis; Antimicrobial activity; 2-amino pyrimidine; 2(L-H) pyrimidinone

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