Abstract
Ph-Metric Studies of Binary and Ternary Complexes of Some Transition Metal Ions With Some Medicinally Important Ligands
A. B. Patil* and T. H. Mhaske
Abstract:
The interaction of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) metal ions with ibuprofen (IBP) and paracetamol (PC) have been studied by pH-metric technique at 0.1 M ionic strength at 29+ 0.5oC. The data obtained were used to evaluate the values of proton-ligand and metal-ligand stability constants. Mixed ligand complex studies of these metal ions using nitrilotriacetic acid (NTA) and iminodiacetic acid (IMDA) as primary ligands and IBP and PC as secondary ligands also have been carried out pH-metrically.
Keywords:pH metry; ternary complexes; ligands
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