Polarographic Determination of Chlordiazepoxide Hydrochloride

N. Y. Sreedhar and S. Jayarama Raddy

Department of Chemistry, Sri Venkateswara University, Tirupati-517 502 A.P. India.

ABSTRACT:

Electrochemical reduction behaviour of chlordiazepoxide hydrochlroide has been studied by employing the advanced electrochemical techniques such as d. c. polarography, cyclic voltammetry, a. c polarography, differential pulse polarography, millicoulometry and controlled potential electrolysis in the supporting electrolytes of pH ranging from 2.0 to 12.0. Kinetic parameters such as diffusion coefficient (D), forward rate constant (K°f, h) values are evaluated and the reduction mechanism is proposed on the basis of the results obtained. A differential pulse pola-rographic method is developed for the quantitative determination of chlordiazepoxide hydlride in pharmaceutical formulations.

KEYWORDS:

Determination; Chlordiazepoxide

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Copy the following to cite this article: Sreedhar N. Y, Raddy S. J. Polarographic Determination of Chlordiazepoxide Hydrochloride. Orient J Chem 1991;7(4).

Copy the following to cite this URL: Sreedhar N. Y, Raddy S. J. Polarographic Determination of Chlordiazepoxide Hydrochloride. Orient J Chem 1991;7(4). Available from: http://www.orientjchem.org/?p=39837