Synthesis and Antibacterial Activity of 1,4-Disubstituted 2-Azetidinone

Faiza Siddieg El-Shafle, Mervat Mustafa El-En Any

Department of Pharmaceutical Chemistry, College of Pharmacy King Saud University, Riyadh, Serndi Arabia

ABSTRACT:

Synthesis of 1,4-disubstituted β-lactam has been accomplished by a Ketene-imine cycloaddition reaction. The effect of -OCH3 and -NO2 groups on the yield have been studied. Also the antibacterial activity of these compounds has been investigated.

KEYWORDS:

Antibacterial; Activity

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Copy the following to cite this article: El-Shafle F. S, Any M. M. E. Synthesis and Antibacterial Activity of 1,4-Disubstituted 2-Azetidinone. Orient J Chem 1988;4(3).

Copy the following to cite this URL: El-Shafle F. S, Any M. M. E. Synthesis and Antibacterial Activity of 1,4-Disubstituted 2-Azetidinone. Orient J Chem 1988;4(3). Available from: http://www.orientjchem.org/?p=41993