3-Nitro-6-Methylbenzene Sulphamido Chalcones and Related Compounds

A. A. El-Maghraby, H. A. Emam, M. T. Shehata, H. A. Eyada and M. K. Badran

Chemistry Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.

ABSTRACT:

3-Nitro-6-methylbenzenesulphamido chalcones (II a, b) were prepared. Interation of sulpha-mido chalcones (II) with hydrazine, phenylhydrazine, urea and thiourea gave the corresponding pyrazole (III) and pyrimidine derivatives (IV). Sulphamido epoxides (VI) reacted readily with hydrazine hydrate, acetic acid or with piperidine and morpholine to give the corresponding hydrosy pyrazole (VII), ∝-hydroxy-β-acetoxy (VIII), oc -hydroxy-β-piperidyl and ∝ -hydroxy-β-morphoyl (IX) respectively. The structure of the prepared compounds was confirmed by analysis, I. R. and H. N. M. R, spectra

KEYWORDS:

Sulphamido; Chalcones; Related; Compounds

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Copy the following to cite this article: El-Maghraby A. A, Emam H. A, Shehata M. T, Eyada H. A, Badran M. K. 3-Nitro-6-Methylbenzene Sulphamido Chalcones and Related Compounds. Orient J Chem 1986;2(1).

Copy the following to cite this URL: El-Maghraby A. A, Emam H. A, Shehata M. T, Eyada H. A, Badran M. K. 3-Nitro-6-Methylbenzene Sulphamido Chalcones and Related Compounds. Orient J Chem 1986;2(1). Available from: http://www.orientjchem.org/?p=42350