Synthesis and Spectral Study of R,R’,4,4’-Cyclohexylidene Diphenyloxy Acetic acids with Antimicrobial Activity

D. R. Bhadja* and P. H. Parsania

¹Department of Chemistry,  M. M. Science College, Morbi - 363 642 (India).

²Department of Chemistry, Saurashtra University, Rajkot - 360 005 (India).

Corresponding author: E-mail: abhidigant@yahoo.com

ABSTRACT:

Synthesis of R,R’,4,4’-cyclohexylidene diphenyloxy acetic acids ( R,R’= H,CH3and Cl) by dissolving  0.1 mole bisphenols in 0.4 mole sodim hydroxide with drop wise addition  of 0.2 mole chloroacetic acid. The reaction mixture refluxed for 4h at 60°C. Phenoxy acids have been confirmed by IR and NMR spectral characterization. The acids are also characterized by their antimicrobial and antifungal activities. The activities have been interpreted in light of bisphenol structures and the nature of substituent(s). The wide scale uses of bisphenol bioactive agents have brought many advantages to the agricultural industries.

KEYWORDS:

Bisphenol; Phenoxy acetic acids; IR; NMR; Antimicrobial screening

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Copy the following to cite this article: Bhadja D. R, Parsania P. H. Synthesis and Spectral Study of R,R’,4,4’-Cyclohexylidene Diphenyloxy Acetic acids with Antimicrobial Activity. Orient J Chem 2011;27(4).

Copy the following to cite this URL: Bhadja D. R, Parsania P. H. Synthesis and Spectral Study of R,R’,4,4’-Cyclohexylidene Diphenyloxy Acetic acids with Antimicrobial Activity. Orient J Chem 2011;27(4). Available from: http://www.orientjchem.org/?p=24274