Preparation Ligand 5-(3-chlorophenyl)-1,3,4-oxadiazole-2-thiol by New Method and Complexation with Transition Metals  

Ahmed S.M. Al-Janabi^¹*, G.A. Al-Soumadaiy^² and Bushra A. Khear-Allah^³

¹Department of Biochemistry, College of Veterinary Medicine, University of Tikrit, Tikrit (Iraq).

²Department of Chemistry, College of Science, University of Tikrit, Tikrit (Iraq).

³Department of Chemistry, College of Education, University of Tikrit, Tikrit (Iraq).

Corresponding Author E-mail: a_sh200683@yahoo.com

ABSTRACT:

A ligand 5-(3-chlorophenyl)-1,3,4-oxadiazol-2-thiol (CPoxSH) synthesized by two methods and its Zn(II), Cd(II), Hg(II), Mn(II), Co(II), and Ni(II) complexes were synthesized. The ligand were prepared by two methods, microwave and classic method, m-chlorobenzol hydrazine(A) was prepared the hydrazinolysis of methyl m-chlorobenzoate(B) with hydrazine hydrate in abs. ethanol. Refluxing of m-chlorobenzol hydrazine(C) in basic medium with carbon disulfide CS2 to give 5-(3-chlorophenyl)-1,3,4-oxadiazol-2-thiol (D). And complexation with [HgX2] ( X= Cl, Br, SCN)(1:1), and [Hg(OAc)2] (1:2) mole proportion of ligand. Reaction of MCl2.xH2O [M(II)= Cd, Zn, Mn, Co, Ni] and [M(OAc)2.xH2O [M = Cd, Zn, Co, Ni] with ligand by (1:2) mole proportion. The preparation ligand and complexes were characterized by element analysis, IR spectral data , 1H  and 13C-{1H} NMR data.

KEYWORDS:

Oxadiazole; Transition metal; Thione; complexes; microwave

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Copy the following to cite this article: Al-Janabi A. S. M, Al-Soumadaiy G. A, Khear-Allah B. A. Preparation Ligand 5-(3-chlorophenyl)-1,3,4-oxadiazole-2-thiol by New Method and Complexation with Transition Metals. Orient J Chem 2011;27(4).

Copy the following to cite this URL: Al-Janabi A. S. M, Al-Soumadaiy G. A, Khear-Allah B. A. Preparation Ligand 5-(3-chlorophenyl)-1,3,4-oxadiazole-2-thiol by New Method and Complexation with Transition Metals. Orient J Chem 2011;27(4). Available from: http://www.orientjchem.org/?p=24170