Synthesis, Characterization, Spectral and Antimicrobial Studies of Fe(III), Co(II), Zn(II), Cd(II), Y(III), and In(III) Complexes of Schiff Base Derived from L-Tryptophan

M.H. Salunke¹, Z.A. Filmwala*, S.B. Dharap¹ and A. D.Kamble¹

*N.S. Research Laboratory, St. Xavier

ABSTRACT:

In the present study 2-Amino-3-(1H-indol-3-yl)-propionic acid hydrazide (AIPAH) (1) has been prepared by reacting earlier reported compound 2-Amino-3-(1H-indol-3-yl)-propionic acid ethyl ester (AIPAEE) with hydrazine hydrate. Schiff base 3-(1H-Indol-3-yl)-2 [(4-methoxy-bezylidene)-amino]-propionic acid(4-methoxy-benzylidene)-hydrazide(IMBAPAMBH) (2) has been synthesized by reacting (1) with 4-methoxy benzaldehyde and its metal complexes with Fe(III), Co(II), Zn(II), Cd(II), Y(III), and In(III) have been prepared. The ligand and metal complexes were characterized on the basis of elemental analysis, IR, NMR spectral data, molar conductance, magnetic susceptibility measurement, thermal analysis (TGA/DTA). Fe(III), Co(II), Y(III), In (III) complexes possesses octahedral and Zn(II), Cd(II) complexes possesses tetrahedral geometry. In vitro antibacterial and antifungal activities of all compounds were tested.

KEYWORDS:

Synthesis; Schiff base; Fe(III); Co(II); Zn(II); Cd(II); Y(III); and In (III) complexes; Antibacterial and antifungal activities

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Copy the following to cite this article: Salunke M. H, Filmwala Z. A, Dharap S. B, Kamble A. D. Synthesis, Characterization, Spectral and Antimicrobial Studies of Fe(III), Co(II), Zn(II), Cd(II), Y(III), and In(III) Complexes of Schiff Base Derived from L-Tryptophan. Orient J Chem 2011;27(3).

Copy the following to cite this URL: Salunke M. H, Filmwala Z. A, Dharap S. B, Kamble A. D. Synthesis, Characterization, Spectral and Antimicrobial Studies of Fe(III), Co(II), Zn(II), Cd(II), Y(III), and In(III) Complexes of Schiff Base Derived from L-Tryptophan. Orient J Chem 2011;27(3). Available from: http://www.orientjchem.org/?p=24601