Synthesis and Characterisation of Glimeperide Complexes of Copper, Magnesium, Nickel and Cadmium

Mohammad Tawkir¹, S. A. Iqbal¹, Bal Krishan¹ and Ishaq Zaafarany²

¹Department of Chemistry, Saifia College of Science and Education, Bhopal - 462001 India. ²Department of Chemistry, Umm-al-Qura University, Makkah-Al-Mukkaramah Saudi Arabia.

ABSTRACT:

Glimeperide, 3-ethyl-4-methyl-N (4[N(1r, 4r)-4-methyl cyclohexyl carbamoyl) sulfamoyl] phnethyl)-2-Oxo-2, 5-dihydro-1-H-pyrrole-1-Carboxamide the recently used hypoglycemic agent is active in NIDDM. Metal complexes of glimeperide have been synthesized by reaction with different metals such as Copper, Magnesium, Nickel and Cadmium in the form of their chloride salts. These complexes were characterised by their physical and analytical data, IR, ¹H NMR and atomic absorption studies.

KEYWORDS:

Antidiabetics; Glimeperide; transition metals; 1H NMR; IR; AA-studies

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Copy the following to cite this article: Tawkir M, Iqbal S. A, Krishan B, Zaafarany I. Synthesis and Characterisation of Glimeperide Complexes of Copper, Magnesium, Nickel and Cadmium. Orient J Chem 2011;27(2).

Copy the following to cite this URL: Tawkir M, Iqbal S. A, Krishan B, Zaafarany I. Synthesis and Characterisation of Glimeperide Complexes of Copper, Magnesium, Nickel and Cadmium. Orient J Chem 2011;27(2). Available from: http://www.orientjchem.org/?p=24982