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Iodine Mediated Mild and Efficient Method for the Synthesis of Tatrahydropyrans Via Cross-Cyclization Between Epoxides and Homoallylic Alcohols

Volume 26, Number 3

J. Madhukar* and S. Nagavani  

Department of Chemistry, Kakatiya University, Warangal - 506 009 (India).

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ABSTRACT:

Epoxides undergo cyclization with homoallylic alcohols in the presence of iodine under mild conditions to afford the corresponding Iodotetrahydropyran derivatives in excellent yields under mild condition.

KEYWORDS:

Epoxides; homoallylic alcohols; tetrahydropyrans; Iodine

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Madhukar J, Nagavani S. Iodine Mediated Mild and Efficient Method for the Synthesis of Tatrahydropyrans Via Cross-Cyclization Between Epoxides and Homoallylic Alcohols. Orient J Chem 2010;26(3).

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Madhukar J, Nagavani S. Iodine Mediated Mild and Efficient Method for the Synthesis of Tatrahydropyrans Via Cross-Cyclization Between Epoxides and Homoallylic Alcohols. Orient J Chem 2010;26(3).Available from: http://www.orientjchem.org/?p=24619

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