ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Evaluation of in Vitro Antispermogenic Activity of Isolated Glycoside and Methanolic Extract of Mangifera Indica L. Roots

Volume 26, Number 3

Biplab De1*, Zerryl Ch. Momin1, Saikat Sen2 and Raja Chakraborty2

1Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala, Tripura - 799 005 (India). 2C.E.S. College of Pharmacy, Chinnatekur, Kurnol, Andra Pradesh - 518 218 (India).

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ABSTRACT:

Metahnolic extract of Mengifera indica L. root produces in vitro antispermogenic activity. In vitro antispermogenic activity of six chromatographic fractions obtained from metahnolic extract of Mengifera indica L. root also performed. Three (M1, M2, M6) out of six fractions showed antispermogenic activity. Among them fraction M6 showed most potent effect observed by percentage decrease in motility. Structure elucidation of M6 showed presence of a glycoside named 1-heptyl-(1-phenyl)-3-xylose benzoate, thus isolated glycoside may responsible for its antispermogenic activity.

KEYWORDS:

Mengifera indica; antispermogenic activity; methanolic extract; glycoside

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De B, Zerryl, Momin C, Sen S, Chakraborty R. Evaluation of in Vitro Antispermogenic Activity of Isolated Glycoside and Methanolic Extract of Mangifera Indica L. Roots. Orient J Chem 2010;26(3).

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De B, Zerryl, Momin C, Sen S, Chakraborty R. Evaluation of in Vitro Antispermogenic Activity of Isolated Glycoside and Methanolic Extract of Mangifera Indica L. Roots. Orient J Chem 2010;26(3). Available from: http://www.orientjchem.org/?p=24535

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