Synthesis, Spectral and Biological Studies of Cr(III), Mn(II) and Fe(II) Complexes With Diacetylmonoxime

A. H. Manikshete, Vaishali N. Kamble, S. K. Sarsamkar and S. Doedware

Materials Science Research Laboratory, Walchand College of Arts and Science, Solapur University, Solapur - 413 006 (India).

A bidentate Schiff base ligand namely diacetylmonoxime2/3-nitroaniline were synthesized by condensing o/m-nitroaniline with diacetylmonoxime. Cr (IIII), Mn (II) and Fe (II) complexes of the chelating ligands were synthesized using chlorides of these metals. The ligands and the complexes were characterised by elemental analysis, spectral (I.R., U.V.-Visible, Mass) analysis, x-ray powder diffraction, magnetic susceptibility measurements. An octahedral structure is proposed for Cr (IIII), Mn (II) and Fe (II) complexes on the basis of magnetic and spectral measurements. Spectroscopic studies indicate that the coordination occurs through oxime oxygen after deprotonation and nitrogen of azomethine. A triclinic system was proposed by x-ray diffraction study of metal complexs. Anti-bacterial and anti-fungal activity of the schiff base ligands and their metal complexes have been studied using the agar well diffusion method and ditch diffusion method. Ligands and metal complexes shows activity against S. aureus (gram positive), P. aeruginosa (gram negative) Aspergillus niger and Candida albicans

Schiff bases; transition metal complexe; Antifungal and antibacterial activity; X-ray powder diffraction study; Triclinic crystal system