Synthesis and Biological Studies of Some Novel Formazans
B. C. Revanasiddappa* and E. V. S. Subrahmanyam
Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences, Paneer, Deralakatee - 574 160 (India).
A new series of formazans (3a-3I) were synthesized containing the INH moiety, INH upon reaction with substituted aromatic aldehydes yields the Schiff bases (2a-2c). Schiff bases on condensation with different diazonium salts will give formazans. The structure of the final newly compounds were assigned on the basis of IR, 1H NMR and MASS spectral data. All the compounds of this series were evaluated for their In-vitro antibacterial and antifungal activity. Some of the compounds showed promising biological activity.
KEYWORDS:Formazans; azo compounds; Schiff bases; anti bacterial and anti fungal activity
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| Copy the following to cite this article: Revanasiddappa B. C, Subrahmanyam E. V. S. Synthesis and Biological Studies of Some Novel Formazans. Orient J Chem 2010;26(1). |
| Copy the following to cite this URL: Revanasiddappa B. C, Subrahmanyam E. V. S. Synthesis and Biological Studies of Some Novel Formazans. Orient J Chem 2010;26(1). Available from: http://www.orientjchem.org/?p=23730 |
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