1, 1-Diphenyl, 2-Picryl Hydrazyl Radical Scavenging Activity of Aqueous Extract of Terminalia Belerica Bark

Akhlesh Singhal¹*, Govind Nayak¹, Ashok Budhwani² and Ahsish Singha²

¹Lakshmi Narain College of Pharmacy, Bhopal (India).

²Daksh Institute of Pharmacy, Chhatarpur (India). ³VNS Institute of Pharmacy, Bhopal (India).

ABSTRACT:

In the present investigation we had attempted to investigate the in vitro antioxidant potential of aqueous extract of Terminalia Billerica bark (TBB). The 1, 1-Diphenyl, 2-picryl hydrazyl assay method had been performed at different doses (100-500 mg). The total phenolic and total flavonoids contents had also been determined. The results of the present study shows that the aqueous extract of TBB possess antioxidant activity through the DPPH free radical scavenging activity. The preliminary phytochemical investigations indicates the presence of flavonoids and polyphones. The results are found to be significant then compared with the standard Ascorbic acid. Further studies are required to determine the mechanism and isolation of active constituents involved in the antioxidant activity.

KEYWORDS:

Terminalia Billerica; DPPH; flavonoids; phenolic contents

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Copy the following to cite this article: Singhal A, Nayak G, Budhwani A, Singha A. 1, 1-Diphenyl, 2-Picryl Hydrazyl Radical Scavenging Activity of Aqueous Extract of Terminalia Belerica Bark. Orient J Chem 2009;25(3).

Copy the following to cite this URL: Singhal A, Nayak G, Budhwani A, Singha A. 1, 1-Diphenyl, 2-Picryl Hydrazyl Radical Scavenging Activity of Aqueous Extract of Terminalia Belerica Bark. Orient J Chem 2009;25(3). Available from: http://www.orientjchem.org/?p=23170