A Convenient Synthesis of Chalcones, Acetylpyrazolines and Aminopyrimidine

Anjani Solankee*, Ghanshyam Patel and Sejal Solankee

Department of Chemistry, B.K.M. Science College, Valsad - 396 001 (India).

ABSTRACT:

Base catalysed condensation of 2-phenylamino-4-(4¹-chlorophenylamino)-6- (4¹-acetylphenylamino)-s-triazine (5) with different substituted aromatic aldehydes give chalcones (6a-e). These Chalcones (6a-e) on cyclisation with hydrazine hydrate in the presence of glacial acetic acid give acetylpyrazolines (7a-e) and with guanidine hydrochloride in the presence of alkali give aminopyrimidines (8a-e). All the synthesised compounds were characterized by IR,1H NMR and physical data.

KEYWORDS:

Chalcones; acetylpyrazolines; aminopyrimidines; spectral data

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Copy the following to cite this article: Solankee A, Patel G, Solankee S. A Convenient Synthesis of Chalcones, Acetylpyrazolines and Aminopyrimidine. Orient J Chem 2008;24(3).

Copy the following to cite this URL: Solankee A, Patel G, Solankee S. A Convenient Synthesis of Chalcones, Acetylpyrazolines and Aminopyrimidine. Orient J Chem 2008;24(3). Available from: http://www.orientjchem.org/?p=25065