Synthesis and Antibacterial Activity of Some New 5-Arylidene Derivatives of 2,3-Diaryl-4-Thiazolidinones

Yogesh Prajapat, Sejal Solankee,Ghanshyam Patel and Anjani Solankee

Department of Chemsitry, B. K. M. Science College, Valsad - 396 001 India.

ABSTRACT:

A series of 2-(phenyl/substituted phenyl/2-furanyl/2""-thienyl)-3-(2',3'-dimethyl-1'-phenyl-3'-pyrazolin-5'-one-4'-yl)-5-[(4-methoxy) benzylidene]-4-thiazolidinones (3a-t) have been synthesized by the reaction between 2,3-diaryl-4-thiazolidinones (2a-t) and 4-methoxy benzaldehyde (1) in alcohol in presence of sodium ethoxide. All the synthesized compounds have been screened for their antibacterial activity. The structures of the syntheiszed compounds have been established on the basis of their elemental analysis and spectral data."

KEYWORDS:

Antibacterial activity; 5-arylidene derivatives; 2,3-diaryl-4-thiazolidinones

Download this article as: 

Copy the following to cite this article: Prajapat Y, Solankee S, Patel G, Solankee A. Synthesis and Antibacterial Activity of Some New 5-Arylidene Derivatives of 2,3-Diaryl-4-Thiazolidinones. Orient J Chem 2008;24(1).

Copy the following to cite this URL: Prajapat Y, Solankee S, Patel G, Solankee A. Synthesis and Antibacterial Activity of Some New 5-Arylidene Derivatives of 2,3-Diaryl-4-Thiazolidinones. Orient J Chem 2008;24(1). Available from: http://www.orientjchem.org/?p=23335