Biotransformation of Some Ring a and B Epoxy Steroids by the Fungus Mucor Plumbeus

Khalid O. Al-Footy

Department of Chemistry, Faculty of Science, King Abdul Aziz University, Jeddah - 21589, P.O. Box 80203 (Saudi Arabia)

ABSTRACT:

The preparation of some ring A and B epoxy steroids derived from testosterone, pregnenolone and epiandrosterone using m-chloroperbenzoic acid is described. The biotransformation of the epoxy products by the fungus Mucor plumbeus are performed. The introduction of the epoxy group into the steroids moiety has affected the biotransformation results and gave only hydrolyzed products.

KEYWORDS:

Mucor plumbeus; Microbiological hydroxylation; expoxy steroids; m-chloroperbenzoic acid

Download this article as: 

Copy the following to cite this article: Al-Footy K. O. Biotransformation of Some Ring a and B Epoxy Steroids by the Fungus Mucor Plumbeus. Orient J Chem 2008;24(1).

Copy the following to cite this URL: Al-Footy K. O. Biotransformation of Some Ring a and B Epoxy Steroids by the Fungus Mucor Plumbeus. Available from: http://www.orientjchem.org/?p=11225