Synthesis of Certain New Azetidin-2-one Derivatives and Comparative Study of Their Biological Activities
Chandramouli1, R. H. Udupi2* and V. Hima Bindu2
1Department of Medicinal Chemistry, NET Pharmacy College, Mantralayam, Road Raichur - 584 103 (India) 2JNT University Kukatpally, Hyderabad - 500 072 (India)
Aryl amines like 4-nitraniline was condensed with 2-amino-3,-dibromo benzaladehyde to get the corresponding Schiff base2. This was reacted with aryloxy acid chlorides to get the required new azetidin-2-one derivatives (3a1-a18). The compounds have been evaluated for antibacterial, antifungal, anti-inflammatory and analgesic activities. Their structures have been elucidated on the basis of elemental analysis and spectral data.
KEYWORDS:Schiff base; aryloxy acid chlorides; azetidinones; antibacterial; antifungal; anti-inflammatory; analgesic activities
Download this article as:
| Copy the following to cite this article: Chandramouli, Udupi R. H, Bindu V. H. Synthesis of Certain New Azetidin-2-one Derivatives and Comparative Study of Their Biological Activities. Orient J Chem 2007;23(3). |
| Copy the following to cite this URL: Chandramouli, Udupi R. H, Bindu V. H. Synthesis of Certain New Azetidin-2-one Derivatives and Comparative Study of Their Biological Activities. Orient J Chem 2007;23(3). Available from: http://www.orientjchem.org/?p=20530 |
This work is licensed under a Creative Commons Attribution 4.0 International License.
About The Author
A New Edition of Web of Science
Journal Impact Factor
2022: 0.5
Five Year: 0.8
Journal is Indexed in
Cabells Whitelist
