ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Synthesis of Novel Derivative of 1,5-Benzothiazepines from 1,3-Diketones and Their Antibacterial Activity

Volume 23, Number 2

N. Kumari, R. K. Saini and Y.C. Joshi*

Department of Chemistry, University of Rajasthan, Jaipur (India)

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ABSTRACT:

Synthesis of 2,4-disubstituted-1, 5-benzothiazepine (2a-e) is reported by the condensation of 2-aminothiophenol (1) with 1,3-diketones in pyridine which posses better pharmacological activity. The structure of newly synthesized compounds have been elucidated by elemental analysis, IR, 1H NMR and 13C NMR spectral studies. Newly synthesized compounds were screened for antibacterial activity.

KEYWORDS:

1;3-diketones; 1;5-benzothiazepines; spectral studies; antibacterial activit

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Kumari N, Saini R. K, Joshi Y. C. Synthesis of Novel Derivative of 1,5-Benzothiazepines from 1,3-Diketones and Their Antibacterial Activity. Orient J Chem 2007;23(2).

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Kumari N, Saini R. K, Joshi Y. C. Synthesis of Novel Derivative of 1,5-Benzothiazepines from 1,3-Diketones and Their Antibacterial Activity. Orient J Chem 2007;23(2). Available from: http://www.orientjchem.org/?p=20313

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