An Unusual Behaviour of A C-N-P Containing Monoarylamide

Mamta Dwivedi and Shashi Prabha

School of Studies in Chemistry, Jiwaji University, Gwalior- 474 001 (India)

Phosphoric-2,5-dimethoxyphenyl amide dichloride is distinct from other C-N-P esters, in showing an exceptionally strong basic nature; the latter aspect being attributed to the presence of two -OCH3 groups. Second order rate coefficients are observed for the hydrolysis proceeding via. Zwitterionic (<0.5 M-HCl); Neutral (0.5-4.0 M-HCl) and conjugate acid species (>5.0 M-HCl) the latter two forms with a proton - sit on the O-OCH3 group too. Biomolecularity and P-N bond cleavage using kinetic variables have been arrived at. The monoamide was synthesized, by direct phosphorylation with POCl3 of the parent amine.

Phosphoric-2;5-dimethoxyphenyl-amide dichloride; C-N-P esters