An Efficient Synthesis of 3,4-Dihydro-2,2-Dimethyl-2h-Pyrano Coumarin Derivatives
P. E. Kumar and K. J. Rajendraprasad*
Department of Chemistry, Bharathiar University, Coimbatore - 641 046 India.
5-Hydroxy-7-methoxy-2,2-dimethyl chroman (1) on condensation with ethyl acetoacetate in the presence of anhydrous aluminium chloride and phosphorous oxychloride gave 5-methoxy-9,10-dihydro-4,8,8-trimethyl pyrano(2,3-h) pyranocoumarin (2) In quantitative yield. The same reaction of hydroxychroman8,3 and 5 afforded the pyranocoumarins4 and 3 respectively. All these products were characterised by spectral means.
KEYWORDS:acetoacetate; hydroxychroman8; respectively
Download this article as:Copy the following to cite this article: Kumar P. E, Rajendraprasad K. J. An Efficient Synthesis of 3,4-Dihydro-2,2-Dimethyl-2h-Pyrano Coumarin Derivatives. Orient J Chem 1998;14(3). |
Copy the following to cite this URL: Kumar P. E, Rajendraprasad K. J. An Efficient Synthesis of 3,4-Dihydro-2,2-Dimethyl-2h-Pyrano Coumarin Derivatives. Orient J Chem 1998;14(3). Available from: |
This work is licensed under a Creative Commons Attribution 4.0 International License.