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Studies on Arylthiophene Heterocycles Part -1 : Synthesis and Biological Activity of Some 2-Aryl/ Arylamino-4- [5-(p-Nitrophenyl)-2-Thienyl)]Thiazoles

Volume 12, Number 2

Balakrishna Kalluraya* and Suresh N. Shetty

Department of Studies in Chemistry, Mangalore University. Mangalagangotri - 574 199 India.

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ABSTRACT:

The preparation of sixteen new 2-aryl/arylamino-4-[5-(p-Nitrophenyl)-2-Thienyl)] thiazoles is described. The new compounds were screened for their antibacterial activity against both Gram-positive and Gram-negativa bacteria. The screening results indicates that compounds carrying the arylamino substituent at the 2-position are more active.

KEYWORDS:

Arylthiophene; Heterocycles;Thiazoles

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Kalluraya B, Shetty S. N. Studies on Arylthiophene Heterocycles Part -1 : Synthesis and Biological Activity of Some 2-Aryl/ Arylamino-4- [5-(p-Nitrophenyl)-2-Thienyl)]Thiazoles. Orient J Chem 1996;12(2).


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Kalluraya B, Shetty S. N. Studies on Arylthiophene Heterocycles Part -1 : Synthesis and Biological Activity of Some 2-Aryl/ Arylamino-4- [5-(p-Nitrophenyl)-2-Thienyl)]Thiazoles. Orient J Chem 1996;12(2). Available from:http://www.orientjchem.org/?p=37752

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