Alcohol-Free Isotropic Solutions of Water/Aerosol -OT/Tween 20/Hydrocarbon

S. Hamdan*, H. Fauziah and F. B. H. Ahmad

Department of Chemistry, Faculty of Science and Environmental Studies, University Pertanian Malaysia, UPM 43400 Serdang, Selangor, Malaysia.

ABSTRACT:

The phase equilibria of water/Aerosol-OT/Tween 20/hydrocarbon systems were investigated to prepare alcohol-free microemulsions for potential use as earners an pharmaceutical applications. The alcohol-free microemulsions were readily formed at variable weight ratio of Aerosol -OT and/or Tween 20 with the hydrocarbon (n-decane and p-xylene) and water. The microemulsion region was found to be dependent not only on the surfactant ratios but also on the nature of the hydrocarbon. Microemulsions containing aromatic hydrocarbon (p-xylene) showed a more defined area compared to microemulsion with aliphatic hydrocarbon(n-decane).

KEYWORDS:

Pharmaceuticals; microemulsion; surfactant; Aerosol-OT; Tween 20

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Copy the following to cite this article: Hamdan S, Fauziah H, Ahmad F. B. H. Alcohol-Free Isotropic Solutions of Water/Aerosol -OT/Tween 20/Hydrocarbon. Chemical Constituents of the Leaves of Zanthoxylum Acanthopodium and its Biological Activity. Orient J Chem 1996;12(2).

Copy the following to cite this URL: Hamdan S, Fauziah H, Ahmad F. B. H. Alcohol-Free Isotropic Solutions of Water/Aerosol -OT/Tween 20/Hydrocarbon. Chemical Constituents of the Leaves of Zanthoxylum Acanthopodium and its Biological Activity. Orient J Chem 1996;12(2). Available from:http://www.orientjchem.org/?p=37763