Synthesis and Chemotherapeutic Evaluation of Some Diazo Coumarins

Alka Pradhan, Vinod Pradhan* & V.S. Jolly

Chemical Laboratories, Government Science & Commerce College, Benazir, Bhopal - 462 001 India.

ABSTRACT:

Ten new azo coumarins have been synthesised using Knoevenagel reaction. A substituted aldehyde was prepared by the condensation of diazotised 0-chloroaniline and salicylaldehyde. New azo coumarins were obtained by the aforesaid reaction of aldehyde and a series of 10 malonanilic acids. These coumarins were screened as antimicrobial and potential carcinostats. Results are encouraging.

KEYWORDS:

Chemotherapeutic Evaluation; Diazo Coumarins; Coumarins

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Copy the following to cite this article: Pradhan Z, Pradhan V, Jolly V. S. Synthesis and Chemotherapeutic Evaluation of Some Diazo Coumarins. Orient J Chem 1994;10(1).

Copy the following to cite this URL: Pradhan Z, Pradhan V, Jolly V. S. Synthesis and Chemotherapeutic Evaluation of Some Diazo Coumarins. Orient J Chem 1994;10(1). Available from:http://www.orientjchem.org/?p=38207