Volume 40, Number 5
Volume 40, Number 5
Phytochemical Profiling and Pharmacological Insights of Haplanthodes tentaculatus (L.) R. B. Majumdar Using GC-MS Analysis
Introduction Plants have played a significant role in medicine since ancient times.1 Ayurveda, which has been practiced in India since its inception, remains the most widely recognized and trusted form of traditional medicine.2,3 One...
Read MoreDevelopment of Modified Pencil Graphite Electrode Sensors by Using Polyaniline and Polypyrrole Based Poly(Acrylamide-Co-Amps) Hydrogels for the Detection of Methylene Blue
Introduction Hydrogels are cross linked three dimensional polymer network systems synthesized via polymerization of monomers which are hydrophilic in nature with the cross linker. The applications of the superabsorbent polymers are employed in super...
Read MoreRevolutionizing Surgical Instrument Reuse: Microbial Action for Nickel Toxicity Removal from Titanium Implements
Introduction Significant progress has been made in the realm of medical science, especially in the area of surgical techniques and procedures 1. Medical professionals now carry titanium-based devices like clockwork, as the need for...
Read MoreThermo-Acoustic Analysis of Molecular Interaction in L-Histidine and K2SO4 Solution at 283 and 293K Temperature Using Ultrasonic Studies
Introduction Ultrasonography has been utilized in several studies to examine the thermos-acoustical characteristics of amino acids 1–8. The ultrasonic technique is a flexible, non-destructive technology that serves as a strong probe to access the...
Read MoreInfluence of Oxidation on the Rheological Parameters of Vegetable Oils
Introduction In the strict sense, the term “lubricating material” refers to the products used to lubricate sliding or rolling tribosystems. However, products similar to them in terms of composition, production processes and properties, but...
Read MoreImproved Hydrogen de/absorption Kinetics of Magnesium (Mg) via Addition of Catalyst Y2O3
Introduction Hydrogen gets attenuation in the whole world due to its dense energy content of 142 MJ/kg, compact, ecofriendly nature, and can easily be produced from water 1. The main problem associates with its...
Read MoreIn-Silico Designing and Synthesis of Small Molecule Potential Inhibitors of Plasmodium falciparum Plasmepsin I Based on HEA and Piperazine Moieties
Introduction Digestive food vacuole of P. falciparum remains equipped with four plasmepsins (PfPlms) plasmepsin I, II IV & Histoaspartic protease (HAP), and they are essentially engaged in the catabolic degradation of hemoglobin during the...
Read MoreSynthesis, Physical, Spectral Characterization and Biological Studies of the complexes of Ni2+,Cu2+, Co2+ and Cd2+ ions with Schiff Base Derived from p-hydroxybenzaldehyde and o-Phenyl-diamine
Introduction Schiff bases have a potential as well as a significant part in inorganic science as they can undoubtedly stable buildings with the majority of the transition metal ions1-6. Specifically, Schiff bases are combined...
Read More2D-QSAR Assisted Design, and Molecular Docking of Novel Indole Derivates as Anti-Cancer Agents
Introduction Cell cycle and apoptosis are two utmost important processes of human cell growth and programmed cell death 1. Cancer is considered a complex disease which occurs when human body fails to regulate these...
Read MoreMaxdo and RDF55v are Crucial Molecular Descriptors Governing the Cannabinoid Receptor 1(CB1) Modulator Activity of N, N’-diphenyl Urea Analogs and 1H-Indole-2-carboxamides
Introduction CB1 constitutes an important target for treating drug addiction, obesity, arthritis, osteoporosis, mental illness, psychosis, and multiple sclerosis1,2. Several agonists/antagonists/inverse agonists have been developed to target these G-protein-coupled receptors. Potent CB agonists like...
Read MoreA Six Sigma Approach to Pharmaceutical Industry- A Better Insight
Introduction Six Sigma is a statistical concept that is used to systematically outline complications, give methods for measuring and identifying influential elements, and provide changes that are simple to apply. Since Motorola adopted it...
Read MoreGreen Fabrication of SnO2 Nanoparticles and Uses as a Powerful Sorbent for Malachite Green Detoxification
Introduction Organic dyes, utilized in various fields, are both toxicants and carcinogens. The toxic effects of organic dyes on humans and the environment exist even at low concentrations. The persistence of organic dyes in...
Read MoreStudy of Metabolites of Cucumis melo subsp. agrestis var conomonby HR-LCMS Q-TOF/MS
Introduction The Cucumis genus includes ornamentals and several regularly grown crops, making it one of the most important genera of flowering plants economically. Cucumis species are distinguished by their bushy, ascending, trailing growth habits1.It...
Read MoreStudies on Metal Complexes of Pyrazole Bearing Ligand with Their Antimicrobial Screening
Introduction Nowadays Metals complexes become very important in the field of medicinal chemistry1,2. The divalent transition metals show various biochemical reactions 3. The researchers synthesised number of metal complexes having organic ligands due to...
Read MoreIn silico Exploration of Quinazolinone-incorporated-chalcones as EGFR Inhibitors (T790M Mutated) to Combat Lung Cancer
Introduction Globally, lung cancer is the most prevalent cancer to be diagnosed and the primary cause of cancer-related mortality1,2. The substantial therapeutic potential of the quinazolinone/quinazoline scaffold was discovered through a review of the...
Read MoreSonochemical Synthesis of Silver Nanoparticles and its Nanomedicinal Activities Against Staphylococcus aureus
Introduction The global outbreak of antibiotic-resistant bacteria and related infectious diseases as a result of indiscriminate intake of commercial antibiotics brought a threat to humans and was considered a serious public health issue1. Infections...
Read MoreDesign, Synthesis, In-Silico and Cytotoxic Studies of Indole derivatives as Potent BCL-2 inhibitors
Introduction The heterocyclic compound indole is a key structural moiety that occurs in a wide range of natural products and synthetic medicinal compounds1,2. Indole exhibits a wide range of biological activities like anticancer 3,4,...
Read MoreAntibacterial Effects of Mo(VI) Macrocyclic Compounds
Introduction A macrocyclic compound must contain at least nine atoms, including all heteroatoms. Three donor atoms must be present in this type of compound. The progress of macrocyclic compounds has accelerated over the past...
Read MoreStudy on Adsorption and Confinement Factors of Non-polar Amino Acids in Alkaline Sandy Loam Soil in the Presence of Fungicide
Introduction A major factor in agricultural sustainability is the preservation or improvement of the health and quality of the soil. In addition to decision regarding agricultural viability, soil quality also affects environmental quality and...
Read MoreKınetıcs of Lıquıd-Phase Process Extractıon of Transıtıon Metals from Ammonıa Solutıons wıth 2-Hydroxy-5-Alkyl Benzylethylenedıamıne
Introduction The extraction method of inorganic transition metal compounds from ammonia solutions and their separation is a relevant and important issue of hydrometallurgy 1–6. The properties of the initial solution and the metals being...
Read MoreCharacterization, Synthesis, and Antimicrobial Activities of Quinazoline Derivatives [EMNEDAQZHO]and their Metal Ion Complexes
Introduction Nitrogen- and sulfur-containing heterocyclic compounds have garnered significant interest due to their extensive therapeutic and pharmacological potential. Among these, quinazoline stands out as a highly promising structure, largely owing to its broad spectrum...
Read MoreBiosynthesis of CuO Nanoparticles using Coleus Aromaticus Leaf Extract for Efficient Catalytic Applications
Introduction In recent decades, nanomaterial synthesis (like graphene, carbon nanotubes, metal nanoparticles, quantum dots, etc.) with dimensions between 10 and 100 nm has drawn attention because of its potential uses in numerous sectors1,2. CuO,...
Read MoreGreen and Eco-friendly Adsorption of Tetracycline using Nano Sized Moringa oleifera: Thermodynamic and kinetic studies
Introduction Environmental pollution caused by industrial waste is a significant concern in recent times.1, 2 Antibiotics have played a crucial role in saving lives over the years by effectively treating bacterial infections.3 Scientists are...
Read MoreA Review on Climatic Change: Causes, Impacts on Wildfires and Human Health
Introduction The climate of the Earth has been exceedingly changing, primarily due to anthropogenic causes that affect all forms of life. Scientists predict that this process also abnormally influences human life and the infrastructure....
Read MoreSynthesis, Bioactivity Screening and Docking Analysis of Thiazole Derivatives Containing Quinoline Moieties
Introduction Due to expansive and repeated uses of antibiotics, drug-resistant and multidrug resistant viral and bacterial infections are increasing in alarming rate that have brought out difficult to treat using previous antibiotic and take...
Read MoreNanoalumina Synthesized from Solanum torvum Leaves: A Green Approach
Introduction Green synthesis employs plant extracts from roots, stems, leaves, floors, and seeds. Flavonoids, alkaloids, phenolics, and others are found in the extracts. Plant extract with metal salts produce nanoparticles of varied sizes, shapes,...
Read MoreSynthesis and Characterization of Li -Zeolite Catalyst for Biodiesel Production from Castor Oil
Introduction Using a stable heterogeneous catalyst can make synthesizing fatty acid methyl esters (FAMEs) through the transesterification of vegetable oils more cost-effective and feasible. This solid catalyst can be easily extracted from the reaction...
Read MoreAssessing the Protective Effects of PC-1 Formulation on Ethanol-Induced Gastric Ulcer Model in Wistar Rats: A Comprehensive Study
Introduction Peptic ulcer disease (PUD) is characterized by the presence of lesions in the gastrointestinal system, which mostly affects the proximal duodenum and the stomach wall. These lesions, which are sometimes referred to as...
Read MoreCa/Al and Ca/Fe as Indicators of Terrigenous and Marine Origin in East Coast Peninsular Malaysia During Holocene
Introduction The Holocene epoch is the geological timescale period from 11,700 years ago to the present, divided into early, mid, and late Holocene1,2,3,4. A gradual increase in sea level after the Last Glacial Maximum...
Read MoreAn Exquisite Design Process and Impacting Synthesis of 2-methyl Nicotinamide Derivatives and their Anti-bacterial Activity Closet to Fab I Inhibitors
Introduction Over the past decade, thousands of infectious diseases[1,2] have been reported around the world, making the development of anti-infective chemotherapeutics more important than ever before. Currently, drug discovery is developing inhibitors of Fab...
Read MoreA Review of the Antioxidant and Antimicrobial Activities and Photoprotective Properties of Psidium guajava L.
Introduction Guava, scientifically known as Psidium guajava L. is a small tree of the Myrtaceae family1. It mostly grows in tropical and subtropical areas in the world2,3. The major phytochemicals of guava are flavonoids,...
Read MoreAdsorption of Amoxicillin using Oxidized Carbon Nanotubes of Aqueous Solution
Introduction The widespread use of antibiotics has become a major concern due to their negative effects on both health and the environment 1, 2. Studies have shown the detection of antibiotics in various aquatic...
Read MoreMethod Development and Validation of Quetiapine Fumerate by Using RP-HPLC
Introduction Quetiapine is an antipsychotic of the atypical type which is most often prescribed for schizophrenia, bipolar disorder and major depressive disorder and it is known as Seroquel, for instance. It is a common...
Read MoreRecent Advancement in the Green Synthesis of Bis(indolyl) Methane via One-pot Multicomponent Condensation Strategy – A Mini Review
Introduction Bis(indolyl)methanes (BIMs) and their derivatives have gained widespread attention as vital nitrogen-containing heterocyclic molecules because they serve as the core structural framework for an array of naturally occurring bioactive compounds1,2. BIMs display a...
Read MoreDesign and Synthesis of Disk-liked Benzotrithiophene Small Molecules for the Organic Solar Cells Material
Introduction As technology rapidly advances, the energy demand continues to grow. Fossil fuels, including natural gas, oil, and coal, are the most consumed energy sources worldwide. However, their limited reserves and the environmental damage...
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