Volume 30, Number 1
Volume 30, Number 1
High Performance Thin Layer Chromatographic Quantification Domperidone and Paracetamol in Tablets Forms Domperidone, Paractamol, Silica gel HPTLC Plate, HPTL
INTRODUCTION Domperidone (DMP, 5-chloro-1-[1-[3-(2-oxo-2,3-dihydro-1H behzimidazol-1-yl)propyl]piperidine-4-yl]-1,3-dihydro-2H-benzimidazol-2-one; Figure 1) is used as an antiemetic drug [1] paractamol (PAR;4-hydroxyacetanilide; Figure2 ) is a centrally and peripherally acting non –opioid analgesics and antipyretic drug [2]. The combination of...
Read MoreReaction of 2-R 5-Oxo 5-H 6- Ethylcarboxylate 7-Phenyl-[1,3,4]Thiadiazolo-[3,2-A]Pyrimidine with Morpholin and their Properties
The diverse and interesting biological activity of thiadiazoleshas been reported 1-4It is well known that these heterocyclesare valuable building blocks. Many methods for preparationof these heterocyclic ring systems and their fused analogues have been described...
Read MoreSynthesis and Bioevaluation of 4-[(2/4-Chloro-/2, 3-Dichloro-/2/4-Bromo-/2, 4-Dinitro-/4-Nitrophenyl) Anilinomethyl]-6-T-Butyl-2h-1-Benzopyran-2-Ones.
Introduction Since a long time, men have been struggling to reduce the adverse effects of pests on crop production and storage by using pesticides. On the other hand, pesticides and their residues are creating...
Read MoreSynthesis, Characterization, and Crystal Structure Determination of a New Indium (III) Complex: [In(5,5’-DiMeBiPy)Cl3(DMSO)].2(DMSO)
Introduction Metal complexes containing 2,2’-bipyridine and phenanthroline ligands have gained importance due of their versatile roles as molecular scaffolding for supramolecular assemblies, and due to their applications in catalysis, electrochemistry biochemistry and ring-opening metathesis...
Read MoreReaction 2-R 5-oxo 5-H 6-Ethylcarboxylate 7-Phenyl -1 ,3,4-Thiadiazolo- [3,2-a] Pyrimidine with Amin
Introduction Condensed derivatives of 1,3,4-thiadiazolo[3,2- a]pyrimidinewere reported to possess a broadspectrum of biological activity1-4, including antibacterial,antitumor, fungicidal, and herbicidal properties. However,thiadiazoles and their condensed analogs are still insufficientlystudied. In continuation of the search for...
Read MoreOrganometallic Derivatives of Ruthenium (II & III) Ligated by Quinazole-2-Thione-4-One.
INTRODUCTION Quinazole-2-thione-4-one (Str. I) contains amide and thioamide groups having interesting donor sites.1 We have reported some complexes of low-valent2 and high-valent3 metal ions with this ligand in our earlier communication. The present paper...
Read MoreEssential Oil Components of German Chamomile Cultivated in Firoozabad, Iran
INTRODUCTION People around the world use between 50,000 to 80,000 flowering plants for medicinal purposes 1. Matricaria recutita L. (syn. M. chamomilla L., Chamomilla recutita L. Rauschert) known as true chamomile or German chamomile is...
Read MoreSynthesis and Characterization of 3-(1-Hydroxy Naphthalene-2-yl)-5-(Furan-2-yl)-1-Substituted Pyrazolines
Introduction The literature survey reveals that pyrazoline derivatives have been studied extensively because of their ready accessibility, diverse chemical reactivity, broad spectrum of biological activity6-8and variety of Industrial applications.9,10 Pyrazolines with sulphonamidoaryl substituent at...
Read MoreSynthesis of N-Citralbenzenaminesbynabh4/B(Oh)3System
Introduction Reduction of α, β-unsaturated carbonyl compounds can follow two pathways: addition to carbonyl group (1,2-reduction) to give allylicproducts or addition to the conjugated double bond (1,4-reduction) to give saturated carbonyl compounds. NaBH4 (common...
Read MoreAn Efficient One-Pot Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions
Introduction Multicomponent reactions play an important role in pharmaceutical industries. Pharmacies are trying to develop green chemistry reactions. Solvent-free synthesis of complex organic structures as drugs is the dream of every pharmacy. Multicomponents reaction...
Read MoreValence Bond Sum (VBS) Analysis on Bis(Dithiocarbamato)Nickel(II) Complexes with Nis4 Chromophore
INTRODUCTION With traditional use of the valence bond sum (VBS) method, the oxidation state of a central atom can be determined if the bond valence parameter (Rij) value and the lengths of the bonds...
Read MoreDft Study on 4(5)-Imidazole-Carbaldehyde-N(5)-Phenylthiosemicarbazone (Imtph): Nmr Shielding Tensors, Thermodynamic Parameters, Nbo Analysis, Molecular Electrostatic Potential (Mep), Homo and Lumo Studies
Introduction Imidazole is an organic compound with the formula C3H4N2. This aromatic heterocyclic is classified as an alkaloid. Imidazole refers to the parent compound whereas imidazoles are a class of heterocycles with similar ring...
Read MoreNaBH4/C: A Convenient System for Reductive Amination of Aldehydes
Introduction The reductive aminationreaction is a suitable procedure for the preparation of amines from their corresponding of aldehydes. Because, other approaches such as: the reduction of nitro, cyano, azide, carboxamide compounds or the alkylation...
Read MoreQuantitative Determination of HIV-Antiviral Agent Using Complexing Reagent in Bulk Material and Formulations
Introduction Abacavir is an antiviral agent which is carbocyclic synthetic nucleoside analogue with inhibitory activity against HIV. The chemical name of Abacavir sulphate is: [(1S, 4R) – 4 – [2 – Amino – 6...
Read MoreA New Method for Synthesis of 2,4,5-Triaryl-1H-Imidazole Derivatives Using SiO2NaHSO4 under Solvent-free Conditions
INTRODUCTION Multicomponent reactions (MCRs) refers to a reaction in which two or more ingredients are combined within a single process and the products they create, which is part of all the components are present1-3....
Read MoreRate Evalution of Graft Copolymerization of Hydrophilic Monomers on to Natural Polymer
Introduction During the past decades, considerable research was being carried out on the graft copolymerization of hydrophilic and hydrophobic vinyl monomers onto polysaccharides. These biodegradable and low cost graft copolymers, with new properties, can...
Read MoreA Multistep Preparation of 3-Aryl-8-Methoxythiazolo [3’, 2’ : 2, 3] [1, 2, 4] Triazino [5, 6-b] Indoles Under Microwave Ir-radiations
Introduction: Bridgehead nitrogen heterocycles containing thiazole and related heterocycles (thiadiazole and thiadiazine) exhibit antihistaminic, antithyroid, antitubercular, antifungal & antibacterial activities1-3 and their synthetic importance has been greatly enhanced by the recent uses of their...
Read MoreGraphene for Preconcentration of Trace Amounts of Ni in Water and Paraffin-Embedded Tissues from Liver Loggerhead Turtles Specimens Prior to flame Atomic Absorption Spectrometry
Introduction Ni at trace concentrations acts as both a micronutrient and a toxicant in marine and fresh water systems (Izatt et al,1991; Izatt et al,1985; Izatt et al,1995; Blake et al,1996; Arca et al,2001;...
Read MoreSynthesis and Characterization of Cu(II), Ni(II) and Co(II) Coordination Compounds with Nitrogen and Oxygen Containing Schiff Base
INTRODUCTION In the last decade, there have been numerous attempts to produce transition metal complexes containing nitrogen and sulphur donor Schiff base ligands. Schiff bases and their metal complexes exhibited biological activity as antiviral1,...
Read MoreReductive Amination of Aldehydes by NaBH4 in the Presence of NaH2PO4.H2O
Introduction The reduction of nitro, cyano, azide, carboxamide compounds is common routes for the synthesis of amines. Also, this goal has been achieved by the alkylation of amines. These methods for the preparation of...
Read MoreAn Efficient and Telescopic Process for Saxagliptin Hydrochloride.
INTRODUCTION Dipeptidyl peptidase-4 (DPP4) is an enzyme, responsible for the inactivation of the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulin tropic polypeptide (GIP). Dipeptidyl peptidase 4 (DPP-4) inhibitors enhance the body’s own ability...
Read MoreBiosuperabsorbent Hydrogel Based on Alginate-g-PolyAA/kaolin Composite for Releasing Cefalexin Drug
INTRODUCTION Composite hydrogels have been of interest to biomaterial scientists for many years because of their hydrophilic character and potential to be biocompatible [1-2]. These networks are special soft and flexible polymeric materials that...
Read MoreAn Efficient Method For The One-Pot, Four-Component Benzaldehyde Based Synthesis of 3-Methyl-1,4-Diphenyl-7,8-Dihydro-1H-Furo[3,4-E]Pyrazolo[3,4-B]Pyridin-5(4H)-Ones Catalyzed by Alum in Environment-Friendly Media.
INTRODUCTION Application of multicomponent reactions (MCRs) to the construction of natural product-based libraries would be most beneficial to this area of research. Such processes in which three or more reactants are combined together in...
Read MoreStudy of Mesoionic Compounds: Synthesis and Pharmacological Evaluation of Several 2-[{(4-Substituted-1-sulphonyl) Sydnon-3-yl}]-1,3,4-thiadiazino(6,5-b)indoles as Antimicrobial, Insecticidal and Antihelmintic Agents
INTRODUCTION An enormous amount of research on synthetic and pharmacological studies of sydnones has been reported during the last few decades1. Mesoionic compounds are non-benzenoid heterocycles containing different combination of hetero atoms. Sydnones being...
Read MoreComparative Study of Isotherms Adsorption of B12 By Single-wall Carbon Nanotube and Multi-wall Carbon Nanotube
Introduction The first serious attempt to understand thestructure of carbons produced by the pyrolysis oforganic materials was made by Rosalind Franklinin the 1950s 1. She showed that these carbons fallinto two distinct classes, which...
Read MoreRecovery of Niobium and Zirconium from the Cyclone Discharge of Chlorination Plant Producing Titanium Tetrachloride
Introduction The chloride route technology for the production of rutile grade TiO2 involves chlorination of the feed stock material mainly beneficiate ilmenite (BI) at high temperature followed by oxidation of the chlorinated product namely...
Read MoreSolvent-Free Microwave Synthesis of Trialkylphosphates
INTRODUCTION Trialkylphosphates are synthesized from alcohols by reaction with reactive phosphorus substances such as phosphorus oxychloride (POCl3), Phosphorus pentachloride (PCl5), and phosphorus pentoxide (P2O5)1,2. The main product of the reaction of alcohol with phosphorus pentachloride...
Read MoreGraftig Copolymerization of Hydrophilic Monomers Onto Alginate for Modification it,s Structure
Introduction The modification of natural polymers is a promising method for the preparation of new materials(1). An efficient approach to modify of natural polymers, in order to synthesis of natural-based SAPs, is graft polymerization...
Read MoreVirgin Coconut Oil Production by Centrifugation Method
Introduction Nowadays, virgin coconut oil (VCO) and olive oil are the most valuable oil. The reason is because they have the potential effects on human health. So, these two types of oils are categorized...
Read MoreComparative Study of Adsorption Isotherms of Vitamin C on Multi wall and single wall Carbon Nanotube
Introduction Nanotubes are categorized as single walled nanotubes (SWNTs) and multi walled nanotubes (MWNTs)[1]. Individual nanotubes naturally align themselves into ropes held together by vanderwaals forces, more specifically, orbital hybridization best describes chemical bonding...
Read MoreIndustrial Effluent Quality of Bikaner District Rajasthan ,India
Introduction Development process and its regular monitoring both are the parallel issues. Bikaner district is situated at NW Rajasthan in India and there are four major heavy industrial area containing thousands of industrial unit...
Read MoreVoltammetric Study and Determination of Phenylephrine Hydrochloride at INP-Nafion-Modified CPE Sensor Employing Differential Pulse Voltammetry
INTRODUCTION Phenylephrine hydrochloride, PHE, (R)-3-hydroxy-α-[(methylamino) methyl] enzenemethanol hydrochloride, is a sympathomimetic drug widely used in the treatment of hypertension , schizophrenia, nasal congestion, sinusitis , rhinitis , and the symptomatic relief of cold symptoms...
Read MoreAnthelmintic Evaluation of Some Novel Synthesized 1, 2, 4-Triazole Moiety Clubbed with Benzimidazole Ring.
INTRODUCTION There are two important types of worm infections, those in which the worms live in the alimentary canal of the host and worms live in other tissues of the host body. Common examples...
Read MoreExtraction of Trace amount Cu(II) by Single Walled Carbon Nanotubes (SWCNTs) in Water Samples and Determination it by FAAS
Introduction Cu at trace concentrations acts as both a micronutrient and a toxicant in marine and fresh water systems [1-8].This element is needed by plants at only very low levels and is toxic at...
Read MoreMethod Development and Validation for Simultaneous Estimation of Olmesartan Medoxomil and Hydrochlorothiazide by Rp-Hplc
Introduction Olmesartan medoxomil(OM) is the latest angiotensin II receptor blocker approved for use as an alternative therapeutic anti-hypertensive agent. Chemically, OM is described as (5- methyl-2- oxo-1, 3- dioxol-4-yl) methyl ester of 4-(1- hydroxy-1-methylethyl)-2-propyl-1-{[2′-(1Htetrazol-...
Read MoreSeparation of Cr(III) from by functionalized Graphene oxide with Covalently Linked Porphyrin (GO–H2NP) Adsorbed on Surfactant Coated C18
Introduction Toxicological studies have proved that the degree of toxicity of an element directly depends on the species in which it is present. Cr(III) is considered as an essential micronutrient for humans and mammals...
Read MoreComparative Study of Antioxidant Activity of Different Extracts and Essential oil Compositions Obtained from Artemisia Sieberi Besser Using Two Different Methods
Introduction Artemisia sieberi Besser, belongs to the Asteraceae family, is a widely distributed plant in Iran [1-2]. In Iranian folk medicine, Artemisia sieberi is introduced to be useful for spasmolytic effects [3-4], vermicide and...
Read MoreOptimization of Sunflower Oil Hydrogenation on Pd-B/γ-Al2O3Catalyst
INTRODUCTION Partial hydrogenation of sunflower oil is an essential process in the oil and fat industries that improves the oxidation stability and thermal properties required for different food and nonfood applications.1, 2 Hydrogenation increases...
Read MoreSynthesis and Characterization of Bioactive Amphiphilic Graft Copolymers with Hydrophilic Poly (1, 3-Dioxolane) Side Chains
Introduction The graft copolymers have received attention recently [1-3], they have many important application [4- 10] in the polymer industry, mainly as surface modifiers for uses as coating, adhesives and dispersants; as compatbilizing agents...
Read MoreEfficiency Investigation of Dye-Sensitized Solar Cells Based on the Zinc Oxide Nanowires
INTRODUCTION Third generation of solar cells is thin-film dye-sensitized with different layers on a substrate like a glass.Among different types of thin–film solar cells,because of their higher efficiency per production costratio compared to the...
Read MoreAn Approach to the Chemosystematics of the Genus Cucumis L.
Introduction Cucurbitaceae is a family of about 120 genera and over 900 species, widely distributed in tropical and subtropical regions of Africa including Madagascar, South, Southeast and East Asia, Australia as well as Central...
Read MoreThermo – Acoustical Studies on Interionic Interactions of Some α-Amino Acids in Aqueous Sucrose Solution at Varying Mass Percentages.
Introduction It is well known that various substances cause changes in the conformation of proteins when present in aqueous-protein solutions. The complex conformational and configurational factors affecting the structure of proteins in solution make...
Read MoreSpectrophotometric Determination of Trace Cyanide in Fruit Wines by the Catalytic Reaction of Ninhydrin Following Micro-Distillation
INTRODUCTION Wine is a natural product, widely consumed in the world with thousands years of tradition and has an obvious commercial value1,2. Wine, in the broader sense, is beverage resulting from the fermentation by...
Read MoreMicrowave Synthesis and Antimicrobial Activity of some Copper (II), Cobalt (II), Nickel (II) and Chromium (III) Complexes with Schiff Base 2, 6-Pyridinedi carboxaldehyde-Thiosemicarbazone
Introduction Microwave irradiation now a day is an accepted tool for accelerating the organic and inorganic reactions. It leads to the higher reaction selectivity and utilization of the inexpensive reagents. In addition to providing...
Read MoreRecovery of Monomer from Nylon waste powder for its Recycling
Introduction Every year thousand tons of polymers are produced in the country and it has been estimated that over 25% of this produce ends up in the municipal disposal sites every year. Nylon account...
Read MoreExtraction of Zn(II) Using Magnetic Chitosan Nanoparticles Grafted with β-cyclodextrin and Determination by FAAS
Introduction The direct determination of trace metals especially toxic metal ions such as Zn, tin, arsenic, lead, antimony and selenium from various samples requires mostly an initial and efficient pre-concentration step [1]. This pre-concentration...
Read MoreIncorporation of Nuclear Wastes in LIP and Uranium Containing LIP Glasses.
Introduction The future development of nuclear energy depends largely on the success of programmes and management of radioactive wastes generated at various stages of the nuclear fuel cycle. A nuclear (radioactive) waste is any...
Read MoreElectrophoresis Profile of Total Peroxidases in Saliva and Sera of Patients with Different Oral Tumors.
INTRODUCTION Peroxidase activity in human body, is found in the exocrine secretions including milk, tears, and saliva as well as in viginal fluid 1,2. Most of this activity is derived from the enzyme synthesized...
Read MoreStructure of Starch-Ionic Surfactant Complexes Studied by Ternary Phase, XRD and Scanning Electron Microscopy
INTRODUCTION The research understanding of polymer/surfactant interactions in aqueous solution has been summarized in several reviews1-4Many investigations have focused on aggregate structure in dilute solution, i.e., system in which phase separation does not occur....
Read MoreBiodegradable Poly(D,L-Lactide)/Lipid Blend Microparticles Prepared by Oil-in-Water Emulsion Method for Controlled Release Drug Delivery
INTRODUCTION Controlled release, prolonged release and sustained release are terms used to refer to drug delivery systems that are produced to deliver precise drug amounts at a pre-programmed rate to achieve the drug level...
Read MoreThe Influence of Tyrozine on Energetic Property in Graphene Oxide: A DFT Studies.
Introduction Nanostructures can be categorized into following forms according to their structures: diamonds with SP3 hybridization, Graphites with SP2 hybridization, Hexagonal diamonds with SP3 hybridization, fullerenes with SP2 hybridization, Nanoparticles, Graphenes, single-layer and multi-layer...
Read MoreEffluents quaity of woolen industrial units and efficiency of wastewater treatment plant at Jorbir, Bikaner, Rajasthan (India)
Introduction The woolen industry of Bikaner is known to be one of the oldest and most revenue generating economic activity. The woolen industrial market “mandi” of Bikaner which is the exclusive one in the...
Read MoreExtraction of Essential Oil from Cinnamon (Cinnamomum Zeylanicum)
Introduction Cinnamomum zeylanicum is one of the oldest herbal medicine known, having been mentioned in Chinese texts since 4 000 years ago [1]. Cinnamomum zeylanicum is an evergreen tropical tree, belonging to the Lauraceae...
Read MoreUnfolding-Induced in Haemoglobin by Exposure to Electromagnetic Fields: a Ftir Spectroscopy Study.
Introduction Several epidemiological studies have reported possible effects on human health from exposure to extremely low frequency electromagnetic field (ELF-EMF). In response to public concern over health effects of EMF exposure, in 1996, the International...
Read MoreEpimerization of Cyclic Alanyl-Alanine in Basic Solutions
INTRODUCTION Epimerization reactions produce diastereomers or epimers1, while racemization is the transformation between enantiomers. However, in some cases 2–5,racemization has been used to meanboth racemization and epimerization. Epimerization and racemization in amino acids, peptides,...
Read MoreSynthetic Approaches to (R)-Cyclohex-2-Enol
Introduction Asymmetric synthesis starting from achiral reactants to produce synthetically useful chiral compounds is an attractive and established branch of synthetic organic chemistry. (R)-cyclohexenol 1 serves as a versatile chiral precursor for synthesis of...
Read More2(3H)Pyrrolone – a Biologically Active Scaffold (A Review)
Introduction Pyrrolones are the five-membered heterocyclic lactams which are either Δ3 (1) or Δ4 (2) derivatives described by several authors1,2. Scheme 1Click here to View Scheme These are also known as pyrrolin-2-ones....
Read More
A New Edition of Web of Science
Journal Impact Factor
2022: 0.5
Five Year: 0.8
Journal is Indexed in
Cabells Whitelist
