ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

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An Explicative Review of Thiadiazole: Medicinal Chemistry Aspects

Abha Mishra, Ekta Khare and Dinesh Chandra


Abstract:

This review examined the biological effects of thiadiazole on humans. In recent years compounds featuring thiadiazole moiety have gained significance in pharmaceutical chemistry. Among the various structural isomers of thiadiazole, 1,3,4-thiadiazole stands out due to its extensive range of pharmacological activities, prompting numerous studies to assess its relevance. The 1,3,4-thiadiazole nucleus is integral to various classes of medications, including antioxidants, antimicrobials, anti-inflammatories, anticonvulsants, and antivirals, among others. In this study, An attempt has been made with recent research finding to review the structural  modification on different derivatives for various pharmacological activities.

Keywords:

Antioxidant; Antimicrobial; Anti-Inflammatory; Anticancer; Biological Activity; Heterocyclic; 1,3,4-thiadiazole; Thiadiazole

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