Meso-Ionic Oxazolones in Heterocyclic Synthesis : Reactions of 4-Arylidene-2-Aryl-Δ2-Oxazolin-5-one With Amino Acids and Some Carbon Nucleophiles

M. A. El-Hashash, A. A. Afify, M. A. Syed, A. Y. Soliman and M. M. Y. Amer

Chemistry Department, Faculty of Science, Ain Shams University. Abbassia, Cairo, Egypt.

ABSTRACT:

Meso-ionic oxazolinonc reacted with aromatic amino acids namely, o, m, and p—aminoben-zoic and gave acrylamide derivatives, some of them were converted to the corresponding benzoxa-zinone derivatives by action of acetic anhydride. With aliphatic amino acids namely glycine and glutamic acid yielded also the corresponding acrylamide derivatives, the latter was converted to a new oxazolinone derivatives via treatment with AcONa or Ac20. Behaviour of these oxazolinones toward arometic hydrocarbons has been investigated.

KEYWORDS:

Meso-Ionic; Heterocyclic; Nucleophiles

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Copy the following to cite this article: El-Hashash M. A, Afify A. A, Syed M. A, Soliman A. Y, Amer M. M. Y. Meso-Ionic Oxazolones in Heterocyclic Synthesis : Reactions of 4-Arylidene-2-Aryl-Δ2-Oxazolin-5-one With Amino Acids and Some Carbon Nucleophilesn. Orient J Chem 1988;4(1).

Copy the following to cite this URL: El-Hashash M. A, Afify A. A, Syed M. A, Soliman A. Y, Amer M. M. Y. Meso-Ionic Oxazolones in Heterocyclic Synthesis : Reactions of 4-Arylidene-2-Aryl-Δ2-Oxazolin-5-one With Amino Acids and Some Carbon Nucleophilesn. Orient J Chem 1988;4(1). Available from: http://www.orientjchem.org/?p=41889