Spectrophotometric Method for Determination of Bambuterol Hydrochloride in Bulk and Tablets

Varun Pawar*, N. Lalitha, S. B. Puranik, P. N. Sanjay Pai and G. K. Rao

Department of Quality Assurance, Al-Ameen College of Pharmacy, Near Lalbagh Main Gate, Bangalore - 560 027 India.

ABSTRACT:

A simple, rapid, precise and accurate spectrophotometric method has been developed for estimation of Bambuterol hydrochloride from tablet formulation. In methanol, Bambuterol showed absorbance in the visible range at 265 nm. Linearity was observed in the concentration range of 40-240 μgmL-1 (r2= 0.9990). The assay results were found to be in good agreement with label claim. The recovery studies were carried out at three different levels i.e. at 80%, 100%, 120%. The method was validated statistically and by recovery studies.

KEYWORDS:

Bambuterol; Spectrophotometry

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Copy the following to cite this article: Pawar V, Lalitha N, Puranik S. B, Pai P. N. S, Rao G. K. Spectrophotometric Method for Determination of Bambuterol Hydrochloride in Bulk and Tablets. Orient J Chem 2008;24(2).

Copy the following to cite this URL: Pawar V, Lalitha N, Puranik S. B, Pai P. N. S, Rao G. K. Spectrophotometric Method for Determination of Bambuterol Hydrochloride in Bulk and Tablets. Orient J Chem 2008;24(2). Available from: http://www.orientjchem.org/?p=24469